製品の概要

  • 製品名Anti-Ku70 + Ku80 antibody
    Ku70 + Ku80 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Ku70 + Ku80
  • 特異性ab53126 detects endogenous levels of total Ku70 + Ku80 proteins.
  • アプリケーション適用あり: WB, IHC-P, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    A synthetic peptide derived from human Ku70 + Ku80.

  • ポジティブ・コントロール
    • LoVo cell extracts and human breast carcinoma tissue.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab53126 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab53126 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
ELISA
  • 追加情報ELISA: 1/20000.
    IHC-P: 1/50 - 1/100.
    WB: 1/300 - 1/1000. Detects bands of approximately 70 and 83 kDa (predicted molecular weight: 70 and 83 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性The Ku autoantigen is a heterodimer of 70kDa (p70) and 80kDa (p80) proteins. The p70 / p80 dimer is important for function of a 460kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. The Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
    • 細胞内局在Nuclear
    • 参照データベース
    • 別名
      • CTC75 antibody
      • CTC85 antibody
      • CTCBF antibody
      • DNA repair protein XRCC5 antibody
      • DNA repair protein XRCC6 antibody
      • G22P1 antibody
      • G22P2 antibody
      • KARP1 antibody
      • Ku 70 antibody
      • Ku 80 antibody
      • Ku 86 antibody
      • Ku86 antibody
      • ML8 antibody
      • NFIV antibody
      • TLAA antibody
      • XRCC5 antibody
      • XRCC6 antibody
      see all

    Anti-Ku70 + Ku80 antibody 画像

    • All lanes : Anti-Ku70 + Ku80 antibody (ab53126) at 1/300 dilution

      Lane 1 : LoVo cell extract
      Lane 2 : LoVo cell extract with immunising peptide


      Predicted band size : 70 , 83 kDa
    • ab53126 at 1/50 dilution staining Ku70 + Ku80 in human breast carcinoma by Immunohistochemistry, Paraffin embedded tissue in the absence and presence of the immunising peptide.

    Anti-Ku70 + Ku80 antibody (ab53126) 使用論文

    ab53126 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab53126.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"