製品の概要

  • 製品名
    Anti-KSHV ORF8 antibody
  • 製品の詳細
    Rabbit polyclonal to KSHV ORF8
  • アプリケーション
    適用あり: WBmore details
  • 免疫原

    Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8.

  • ポジティブ・コントロール
    • TPA-induced BCBL-1 cell lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: 0.05% Sodium azide
    Constituent: PBS
  • 精製度
    Whole antiserum
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab36599 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 68 kDa.

ターゲット情報

  • 関連性
    Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.
  • 別名
    • HHV 8 antibody
    • Human herpesvirus 8 antibody
    • Kaposi's sarcoma herpes virus antibody
    • KSHV antibody
    • ORF8 antibody
    see all

画像

  • All lanes : Anti-KSHV ORF8 antibody (ab36599)

    Lane 1 : Uninduced BCBL-1 cell lysate
    Lane 2 : TPA induced BCBL-1 cell lysate
    Lane 3 : Purified virion

プロトコール

参考文献

This product has been referenced in:
  • Lin X  et al. MicroRNAs and unusual small RNAs discovered in Kaposi's sarcoma-associated herpesvirus virions. J Virol 86:12717-30 (2012). Read more (PubMed: 22973026) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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