製品の概要

  • 製品名Anti-KMT2H / ASH1 antibody [ASH5H03]
    KMT2H / ASH1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [ASH5H03] to KMT2H / ASH1
  • アプリケーション適用あり: Dot blot, WBmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Recombinant fragment corresponding to Human KMT2H/ ASH1 aa 1611-1728.
    Sequence:

    IGSCRVSNPNSSGRKKLTDSPGLFSAQDTSLNRLHRKESLPSNERAVQTL AGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTVNGVPSRSPRLVASG DDSVDSLLQRMVQNEDQE

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservative: 0.05% Sodium Azide
    Constituents: 1% BSA, PBS, 8mM Sodium phosphate, 3mM Potassium chloride, 140mM Sodium chloride, 1.5mM Potassium phosphate, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)ab50981 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum
  • ポリ/モノモノクローナル
  • クローン名ASH5H03
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab50981 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Dot blot
WB
  • 追加情報Dot: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 330 kDa.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Histone methyltransferase. Probably methylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation.
    • 組織特異性Widely expressed, with highest level in brain, heart and kidney.
    • 配列類似性Belongs to the histone-lysine methyltransferase family. SET2 subfamily.
      Contains 3 A.T hook DNA-binding domains.
      Contains 1 AWS domain.
      Contains 1 BAH domain.
      Contains 1 bromo domain.
      Contains 1 PHD-type zinc finger.
      Contains 1 post-SET domain.
      Contains 1 SET domain.
    • 細胞内局在Nucleus. Cell junction > tight junction. Chromosome. The relevance of tight junction localization is however unclear.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Absent small and homeotic disks protein 1 homolog antibody
      • Absent Small or Homeotic Like antibody
      • Absent Small or Homeotic Like antibody
      • ASH 1 antibody
      • ASH 1L antibody
      • ash1 (absent small or homeotic 1) antibody
      • Ash1 (absent small or homeotic) like antibody
      • ASH1-like protein antibody
      • ASH1L antibody
      • ASH1L_HUMAN antibody
      • ASH1L1 antibody
      • FLJ10504 antibody
      • huASH1 antibody
      • KIAA1420 antibody
      • Lysine N-methyltransferase 2H antibody
      • Probable histone-lysine N-methyltransferase ASH1L antibody
      see all

    Anti-KMT2H / ASH1 antibody [ASH5H03] 画像

    Anti-KMT2H / ASH1 antibody [ASH5H03] (ab50981) 使用論文

    This product has been referenced in:
    • Atta H  et al. Mutant MMP-9 and HGF gene transfer enhance resolution of CCl4-induced liver fibrosis in rats: role of ASH1 and EZH2 methyltransferases repression. PLoS One 9:e112384 (2014). Dot blot . Read more (PubMed: 25380300) »

    See 1 Publication for this product

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    There are currently no Abreviews or Questions for ab50981.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"