製品の概要
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製品名Anti-KLRA2 antibody
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製品の詳細Rabbit polyclonal to KLRA2
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由来種Rabbit
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アプリケーション適用あり: ICC/IF, WB, IHC-Pmore details
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種交差性交差種: Mouse, Rat
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免疫原
14 amino acid synthetic peptide near the C-terminus of Mouse KLRA2
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ポジティブ･コントロール
- Mouse spleen tissue lysate, Human spleen tissue
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at 4°C (stable for up to 12 months).
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バッファーPreservative: 0.02% Sodium Azide
Constituents: PBS -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab107510 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| ICC/IF | Use a concentration of 20 µg/ml. | |
| WB | Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 34 kDa. | |
| IHC-P | Use a concentration of 2.5 µg/ml. |
ターゲット情報
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関連性KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells.
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細胞内局在Membrane
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参照データベース
- Entrez Gene: 16633 Mouse
- Entrez Gene: 494194 Rat
- SwissProt: Q60660 Mouse
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別名
- Ly49-b antibody
- Killer cell lectin-like receptor 2 antibody
- Klra2 antibody
see all
画像
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Western blot - KLRA2 antibody (ab107510)Lane 1 : Anti-KLRA2 antibody (ab107510) at 0.5 µg/ml
Lane 2 : Anti-KLRA2 antibody (ab107510) at 1 µg/ml
All lanes : Mouse spleen tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 34 kDa -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - KLRA2 antibody (ab107510)Immunohistochemistry of KLRA2 in paraffin embedded mouse spleen tissue with ab107510 at 2.5 µg/ml.
プロトコール
参考文献
ab107510 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"