製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to KLLN
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 143-171 of Human KLLN (NP_001119521.1).

  • ポジティブ・コントロール
    • MDA-MB435 cell line lysates.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab110756 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 20 kDa.

ターゲット情報

  • 機能
    DNA-binding protein involved in S phase checkpoint control-coupled apoptosis by mediating p53/TP53-induced apoptosis. Has the ability to inhibit DNA synthesis and S phase arrest coupled to apoptosis. Has affinity to both double- and single-stranded DNA.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CWS4 antibody
    • KILIN_HUMAN antibody
    • Killin antibody
    • Killin, p53-regulated DNA replication inhibitor antibody
    • KLLN antibody
    see all

画像

  • Anti-KLLN antibody (ab110756) at 1/100 dilution + MDA-MB435 cell line lysates at 35 µg

    Predicted band size : 20 kDa

プロトコール

参考文献

This product has been referenced in:
  • Nizialek EA  et al. Germline and somatic KLLN alterations in breast cancer dysregulate G2 arrest. Hum Mol Genet 22:2451-61 (2013). Human . Read more (PubMed: 23446638) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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