製品の概要

  • 製品名Anti-KLHL21 antibody
  • 製品の詳細
    Rabbit polyclonal to KLHL21
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Recombinant fragment corresponding to a region within amino acids 345-520 of Human KLHL21

  • ポジティブ・コントロール
    • WB: A549, HeLa, Jurkat and Raji whole cell lysates IHC-P: Hepatoma tissue

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab111604 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 67 kDa.
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with 10mM citrate buffer pH 6.0 or Tris-EDTA buffer pH 8.0 before commening with IHC staining protocol.

ターゲット情報

  • 機能Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome.
  • パスウェイProtein modification; protein ubiquitination.
  • 配列類似性Contains 1 BACK (BTB/Kelch associated) domain.
    Contains 1 BTB (POZ) domain.
    Contains 6 Kelch repeats.
  • 細胞内局在Cytoplasm > cytoskeleton > spindle. Localizes to the spindle midzone and targets CUL3 to this region.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Kelch-like protein 21 antibody
    • KIAA0469 antibody
    • KLH21_HUMAN antibody
    • KLHL21 antibody
    • MGC99635 antibody
    see all

Anti-KLHL21 antibody 画像

  • Anti-KLHL21 antibody (ab111604) at 1/1000 dilution + A549 whole cell lysate at 30 µg

    Predicted band size : 67 kDa
  • ab111604, at a 1/500, staining KLHL21 in paraffin-embedded Hepatoma tissue.

Anti-KLHL21 antibody (ab111604) 使用論文

ab111604 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"