製品の概要

  • 製品名Anti-Kir4.1 antibody
    Kir4.1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Kir4.1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Horse, Cow, Human, Macaque Monkey, Gorilla, Chinese Hamster
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 300 to the C-terminus of Human Kir4.1.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Mouse Spinal cord tissue lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab101064 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).

ターゲット情報

  • 機能May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). In the kidney, together with KCNJ16, mediates basolateral K(+) recycling in distal tubules; this process is critical for Na(+) reabsorption at the tubules.
  • 組織特異性Expressed in kidney (at protein level).
  • 関連疾患Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance
  • 配列類似性Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ10 subfamily.
  • 細胞内局在Membrane. Basolateral cell membrane. In kidney distal convoluted tubules, located in the basolateral membrane where it colocalizes with KCNJ16.
  • Information by UniProt
  • 参照データベース
  • 別名
    • inwardly rectifying subfamily J member 10 antibody
    • ATP dependent inwardly rectifying potassium channel Kir4.1 antibody
    • ATP sensitive inward rectifier potassium channel 10 antibody
    • ATP-dependent inwardly rectifying potassium channel Kir4.1 antibody
    • ATP-sensitive inward rectifier potassium channel 10 antibody
    • BIRK10 antibody
    • Glial ATP dependent inwardly rectifying potassium channel KIR4.1 antibody
    • Inward rectifier K(+) channel Kir1.2 antibody
    • Inward rectifier K+ channel KIR1.2 antibody
    • Inwardly rectifying potassium channel Kir1.2 antibody
    • KCJ10_HUMAN antibody
    • KCNJ 10 antibody
    • Kcnj10 antibody
    • KCNJ13 PEN antibody
    • KIR1.2 antibody
    • KIR4.1 antibody
    • Potassium channel antibody
    • Potassium channel inwardly rectifying subfamily J member 10 antibody
    • Potassium inwardly rectifying channel subfamily J member 10 antibody
    • SESAME antibody
    see all

Anti-Kir4.1 antibody 画像

  • Anti-Kir4.1 antibody (ab101064) at 1 µg/ml + Spinal Cord (Mouse) Tissue Lysate at 10 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 42 kDa


    Exposure time : 8 minutes

Anti-Kir4.1 antibody (ab101064) 使用論文

ab101064 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab101064.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"