製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to Kir2.2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 360-409 (KDLVENKFLL PSANSFCYEN ELAFLSRDEE DEADGDQDGR SRDGLSPQAR) of Human Kir2.2 (NP_066292).

  • ポジティブ・コントロール
    • Human fetal brain lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab84972 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 49 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
  • 配列類似性
    Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ATP sensitive inward rectifier potassium channel 12 antibody
    • ATP-sensitive inward rectifier potassium channel 12 antibody
    • hIRK antibody
    • Human high conductance inward rectifier potassium channel alpha antibody
    • Inward rectifier K antibody
    • Inward rectifier K(+) channel Kir2.2 antibody
    • Inward rectifier K(+) channel Kir2.2v antibody
    • inwardly rectifying subfamily J member 12 antibody
    • IRK-2 antibody
    • IRK12_HUMAN antibody
    • IRK2 antibody
    • KCNJ12 antibody
    • kcnj12x antibody
    • KCNJN1 antibody
    • Kir2.2v antibody
    • Potassium channel antibody
    • Potassium channel inwardly rectifying subfamily J member 12 antibody
    • Potassium inwardly rectifying channel subfamily J member 12 antibody
    • Potassium inwardly rectifying channel,subfamily J inhibitor 1 antibody
    see all

画像

  • Anti-Kir2.2 antibody (ab84972) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal brain lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 49 kDa
    Observed band size : 49 kDa
    Gel concentration: 12%


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Heart Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Liver Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Lung Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Muscle Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Pancreas Lysate


  • Predicted band size : 49 kDa
    Western Blot using ab84972 at 1.0ug/ml. Sample type: Hum. Fetal Stomach Lysate

プロトコール

参考文献

ab84972 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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