製品の概要

  • 製品名Anti-KIF5B antibody [SUK-4]
    KIF5B 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [SUK-4] to KIF5B
  • 特異性This antibody recognizes an epitope at the C terminus of the motor domain.
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Rat, Cow, Human, Drosophila melanogaster, Sea Urchin
  • 免疫原

    Full length native protein (purified) corresponding to KIF5B.

  • 特記事項


    This antibody inhibits kinesin induced microtubule translocation in in vitro motility assays. Kinesin heavy chain localizes to sites of vesicular trafficking, especially microtubule pathways in neuronal cells and the Golgi in cultured non neuronal cell types.

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.03% Thimerosal (merthiolate).
    Constituents: PBS.
  • Concentration information loading...
  • 精製度Protein G purified
  • 一次抗体 備考This antibody inhibits kinesin induced microtubule translocation in in vitro motility assays. Kinesin heavy chain localizes to sites of vesicular trafficking, especially microtubule pathways in neuronal cells and the Golgi in cultured non neuronal cell types.
  • ポリ/モノモノクローナル
  • クローン名SUK-4
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab28060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 120 kDa.
ICC/IF 1/500 - 1/1000. PubMed: 19743964

ターゲット情報

  • 機能Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
  • 配列類似性Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily.
    Contains 1 kinesin motor domain.
  • ドメインComposed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.
  • 細胞内局在Cytoplasm, cytoskeleton. Uniformly distributed between soma and neurites in hippocampal neurons.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Conventional kinesin heavy chain antibody
    • KIF 5B antibody
    • KIF5B antibody
    • Kinesin 1 antibody
    • kinesin 1 (110-120kD) antibody
    • Kinesin 1 heavy chain antibody
    • Kinesin family member 5B antibody
    • Kinesin heavy chain antibody
    • kinesin, heavy chain, ubiquitous antibody
    • Kinesin-1 heavy chain antibody
    • Kinesin1 antibody
    • KINH antibody
    • KINH_HUMAN antibody
    • KNS 1 antibody
    • KNS antibody
    • KNS1 antibody
    • Ubiquitous kinesin heavy chain antibody
    • UKHC antibody
    see all

Anti-KIF5B antibody [SUK-4] 画像

  • Ab28060, at a dilution of 1/100, staining KIF5B in MeOH fixed HeLa cells by Immunofluorescence.

Anti-KIF5B antibody [SUK-4] (ab28060) 使用論文

This product has been referenced in:
  • Kathleen Baxter K  et al. The neurogenic basic helix-loop-helix transcription factor NeuroD6 concomitantly increases mitochondrial mass and regulates cytoskeletal organization in the early stages of neuronal differentiation. ASN Neuro 1: (2009). WB, ICC/IF ; Rat . Read more (PubMed: 19743964) »

See 1 Publication for this product

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Thank you for your reply.


I am glad there is another construct available for you to work with. I wish you the best of luck with your experiments!


Please do not hesitate to contact me if I can be of any further assistance.

Thank you for contacting Abcam regarding ab28060.


Unfortunately we have not mapped the specific epitope for this monoclonal antibody and thus we do not know which part of the protein is specifically recognized by it. The antibody was ra...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"