製品の概要

  • 製品名Anti-KIF5B antibody [KN-02]
    KIF5B 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [KN-02] to KIF5B
  • 特異性The antibody reacts with heavy chain of conventional kinesin associated with vesicles and with lower affinity with denaturated molecule. The antibody does not react with kinesin bound to taxol-stabilized microtubules.
  • アプリケーション適用あり: ICCmore details
  • 種交差性
    交差種: Mouse, Rat, Human, Pig
  • 免疫原

    Enriched fraction of porcine brain kinesin.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab11882 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC Use at an assay dependent dilution.

ターゲット情報

  • 機能Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes.
  • 配列類似性Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. Kinesin subfamily.
    Contains 1 kinesin motor domain.
  • ドメインComposed of three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles.
  • 細胞内局在Cytoplasm, cytoskeleton. Uniformly distributed between soma and neurites in hippocampal neurons.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Conventional kinesin heavy chain antibody
    • KIF 5B antibody
    • KIF5B antibody
    • Kinesin 1 antibody
    • kinesin 1 (110-120kD) antibody
    • Kinesin 1 heavy chain antibody
    • Kinesin family member 5B antibody
    • Kinesin heavy chain antibody
    • kinesin, heavy chain, ubiquitous antibody
    • Kinesin-1 heavy chain antibody
    • Kinesin1 antibody
    • KINH antibody
    • KINH_HUMAN antibody
    • KNS 1 antibody
    • KNS antibody
    • KNS1 antibody
    • Ubiquitous kinesin heavy chain antibody
    • UKHC antibody
    see all

Anti-KIF5B antibody [KN-02] 画像

  • Immunofluorescence staining of vesicles (red) in RBL-2H3 rat basophilic leukemia cell line using anti-KIF5B (ab11882). Nuclei were stained with DAPI (blue).

Anti-KIF5B antibody [KN-02] (ab11882) 使用論文

ab11882 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab11882.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"