製品の概要

  • 製品名
    Anti-KIF3A antibody [K2.4]
    KIF3A 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [K2.4] to KIF3A
  • 特異性
    ab24626 appears to react with epitopes on the 85 subunit (KIF3A) of kinesin II lying outside the conserved motor domain.
  • アプリケーション
    適用あり: Blocking, ICC/IF, WBmore details
  • 種交差性
    交差種: Rat, Xenopus laevis, Sea urchin
    交差が予測される動物種: Mammal
  • 免疫原

    Full length native protein (purified)- kinesin II purified from unfertilized sea urchin egg cytosol.

  • 特記事項


    The antibody blocks ciliogenesis in urchin eggs.

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab24626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Blocking Use at an assay dependent dilution. It blocks ciliogenesis in urchin eggs.
ICC/IF Use at an assay dependent dilution.
WB 1/1000. Predicted molecular weight: 85-95 kDa.

ターゲット情報

  • 機能
    Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro.
  • 配列類似性
    Belongs to the kinesin-like protein family. Kinesin II subfamily.
    Contains 1 kinesin-motor domain.
  • 細胞内局在
    Cytoplasm > cytoskeleton.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KIF 3 antibody
    • KIF 3A antibody
    • KIF3 antibody
    • Kif3a antibody
    • KIF3A_HUMAN antibody
    • Kifl antibody
    • Kinesin family member 3A antibody
    • Kinesin family protein 3 antibody
    • Kinesin family protein 3A antibody
    • Kinesin like protein KIF 3A antibody
    • Kinesin like protein KIF3A antibody
    • Kinesin-like protein KIF3A antibody
    • Kns3 antibody
    • Microtubule plus end directed kinesin motor 3A antibody
    • Microtubule plus end-directed kinesin motor 3A antibody
    see all

画像

  • Immunofluorescence analysis of rat hippocampal neurons, staining KIF3A with ab24626 at 1/500 dilution.

    Neurons were fixed in paraformaldehyde at 4°C for 20 minutes before incubation with the primary antibody. An AlexaFluor®-conjugated anti-mouse IgG was used as the secondary antibody (1/1000).

参考文献

This product has been referenced in:
  • Schwamborn JC  et al. The interaction of mPar3 with the ubiquitin ligase Smurf2 is required for the establishment of neuronal polarity. J Biol Chem 282:35259-68 (2007). WB, IF ; Rat . Read more (PubMed: 17906294) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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