Anti-KIF21B 抗体 (ab121931)
Key features and details
- Rabbit polyclonal to KIF21B
- Suitable for: ICC/IF, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-KIF21B antibody -
製品の詳細
Rabbit polyclonal to KIF21B -
由来種
Rabbit -
アプリケーション
適用あり: ICC/IF, IHC-Pmore details -
種交差性
交差種: Human -
免疫原
antigen: RKTQEVSALR RLAKPMSERV AGRAGLKPPM LDSGAEVSAS TTSSEAESGA RSVSSIVRQW NRKINHFLGD HPAPTVNGTR PARKKFQKKG, corresponding to amino acids 814-903 of Human KIF21B.
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ポジティブ・コントロール
- Human kidney tissue.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab121931の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ICC/IF |
Use a concentration of 1 - 4 µg/ml.
Recommend PFA Fixation and Triton X-100 treatment |
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IHC-P |
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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ICC/IF
Use a concentration of 1 - 4 µg/ml. Recommend PFA Fixation and Triton X-100 treatment |
IHC-P
1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
Microtubule-binding motor protein probably involved in neuronal dendritic transport. In vitro, has a plus-end directed motor activity. -
配列類似性
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.
Contains 7 WD repeats. -
細胞内局在
Cytoplasm > cytoskeleton. - Information by UniProt
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参照データベース
- Entrez Gene: 23046 Human
- Omim: 608322 Human
- SwissProt: O75037 Human
- Unigene: 169182 Human
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別名
- KI21B_HUMAN antibody
- KIAA0449 antibody
- KIF21B antibody
- Kinesin-like protein KIF21B antibody
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab121931 は 2 報の論文で使用されています。
- Liu B et al. Targeting kinesin family member 21B by miR-132-3p represses cell proliferation, migration and invasion in gastric cancer. Bioengineered 13:9006-9018 (2022). PubMed: 35341446
- Sun ZG et al. Kinesin superfamily protein 21B acts as an oncogene in non-small cell lung cancer. Cancer Cell Int 20:233 (2020). PubMed: 32536821