製品の概要

  • 製品名Anti-KIAA1967 antibody
    KIAA1967 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KIAA1967
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Horse, Guinea pig, Cow, Dog, Pig, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residues 1 and 50 of Human KIAA1967 (UniProt: Q8N163).

  • ポジティブ・コントロール
    • Human: breast carcinoma, colon carcinoma, metastatic lymph node, ovarian carcinoma, pancreatic islet cell tumor, skin basal cell carcinoma, stomach adenocarcinoma, testicular seminoma. Mouse: squamous cell carcinoma.
  • 特記事項

    Concentration is optimized for IHC and not determined

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84384 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/100 - 1/500. Epitope exposure with citrate buffer will enhance staining.
    Note: expected to work on frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.
    • 組織特異性Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CCAR2 antibody
      • Cell cycle and apoptosis regulator 2 antibody
      • Cell division cycle and apoptosis regulator protein 2 antibody
      • DBC-1 antibody
      • DBC.1 antibody
      • DBC1 antibody
      • DBIRD complex subunit KIAA1967 antibody
      • Deleted in breast cancer 1 antibody
      • Deleted in breast cancer gene 1 protein antibody
      • K1967_HUMAN antibody
      • KIAA1967 antibody
      • NET35 antibody
      • p30 DBC antibody
      • p30 DBC protein antibody
      • p30DBC antibody
      see all

    Anti-KIAA1967 antibody 画像

    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human breast tumor tissue using 1/250 ab84384, followed by DAB staining.
    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Mouse squamous cell carcinoma tissue using 1/250 ab84384, followed by DAB staining.

    Anti-KIAA1967 antibody (ab84384) 使用論文

    This product has been referenced in:
    • Cha EJ  et al. Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma. Clin Cancer Res 15:4453-9 (2009). Read more (PubMed: 19509139) »

    See 1 Publication for this product

    Product Wall

    Vielen Dank für Ihre Anfrage.
    Leider gibt der Hersteller dieses Antikörpers keine genauen Konzentrationsangaben weiter.
    Ich möchte Sie deshalb bitten eine Konzentration von ca. 1mg/ml anzunehmen, falls Sie eine Isotypen-Kontrolle verwenden. <...

    Read More

    Vielen Dank für Ihre Anfrage. Ich kann Ihnen nun bestätigen, dass ab84384 (Anti-DBC1 antibody) eine Konzentration von ca. 1mg/ml hat. Außerdem kann ich Ihnen bestätigen, dass das Lot, das im Moment von ab114033 (Anti-CD26 antibody [11D7]) vorrätig i...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"