製品の概要

  • 製品名Anti-KIAA1967 antibody
    KIAA1967 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KIAA1967
  • アプリケーション適用あり: WB, IPmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Dog, Pig, Chimpanzee, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region between residues 650 and 700 of Human KIAA1967 (UniProt: Q8N163)

  • ポジティブ・コントロール
    • Nuclear extract from HeLa cells.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70240 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 120 kDa (predicted molecular weight: 103 kDa).
IP Use at 1-10 µg/mg of lysate.

ターゲット情報

  • 機能Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis. Inhibits SUV39H1 methyltransferase activity.
  • 組織特異性Expressed ubiquitously in normal tissues. Expressed in 84 to 100% of neoplastic breast, lung, and colon tissues.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CCAR2 antibody
    • Cell cycle and apoptosis regulator 2 antibody
    • Cell division cycle and apoptosis regulator protein 2 antibody
    • DBC-1 antibody
    • DBC.1 antibody
    • DBC1 antibody
    • DBIRD complex subunit KIAA1967 antibody
    • Deleted in breast cancer 1 antibody
    • Deleted in breast cancer gene 1 protein antibody
    • K1967_HUMAN antibody
    • KIAA1967 antibody
    • NET35 antibody
    • p30 DBC antibody
    • p30 DBC protein antibody
    • p30DBC antibody
    see all

Anti-KIAA1967 antibody 画像

  • Lanes 1 - 2 : Anti-KIAA1967 antibody (ab70240) at 1/1000 dilution
    Lanes 3 - 4 : Anti-KIAA1967 antibody (ab70240) at 1/10000 dilution

    Lane 1 : Nuclear extract from HeLa cells at 15 µg
    Lane 2 : Nuclear extract from HeLa cells at 45 µg
    Lane 3 : Nuclear extract from HeLa cells at 15 µg
    Lane 4 : Nuclear extract from HeLa cells at 45 µg

    Developed using the ECL technique

    Predicted band size : 103 kDa


    Exposure time : 5 seconds

Anti-KIAA1967 antibody (ab70240) 使用論文

ab70240 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab70240.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"