製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to KIAA1543
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    antigen sequence: LRHQPILMGA HLAVIDALMA AFAFEWTKTL PGPLALTSLE HKLLFWVDTT VRRLQEKTEQ EAAQRASPAA PADGAAPAQP SIRYRKDR, corresponding to amino acids 127-214 of Human KIAA1543 isoform 1 (Q9P1Y5).

  • ポジティブ・コントロール
    • Human colon tissue.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab122864 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能
    Microtubule minus-end binding protein that acts as a regulator of microtubule dynamics. Specifically required for zonula adherens biogenesis and maintenance by anchoring microtubules at their minus-ends to zonula adherens, leading to recruit KIFC3 kinesin to junctional site.
  • 配列類似性
    Belongs to the CAMSAP1 family.
    Contains 1 CH (calponin-homology) domain.
    Contains 1 CKK domain.
  • ドメイン
    The CKK domain binds microtubules.
  • 細胞内局在
    Cell junction > adherens junction. Cytoplasm. Cytoplasm > cytoskeleton. Scattered in the cytoplasm. Localizes along zonula adherens only at mature cell-cell contacts.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Calmodulin regulated spectrin associated protein family, member 3 antibody
    • Calmodulin-regulated spectrin-associated protein 3 antibody
    • CAMP3_HUMAN antibody
    • KIAA1543 antibody
    • NEZHA antibody
    • Protein Nezha antibody
    see all

画像

  • ab122864 at 1/50 dilution staining KIAA1543 in paraffin-embedded Human colon tissue by Immunohistochemistry.

プロトコール

参考文献

ab122864 has not yet been referenced specifically in any publications.

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