製品の概要

  • 製品名Ketotifen fumarate
  • 製品の詳細
    Selective, H1 antagonist
  • 生理活性の詳細Selective, non-competitive H1 antagonist. Inhibits phosphodiesterases and blocks Ca2+ channels.
  • 精製度> 99%

製品の特性

  • 体系名4,9-Dihydro-4-(1-methylpiperidin-4-ylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate
  • 分子量425.50
  • 構造式Chemical Structure
  • 分子式C19H19NOS.C4H4O4
  • CAS 番号34580-14-8
  • 保存方法Store at Room Temperature. The product can be stored for up to 12 months.
  • 溶解性Soluble in DMSO to 100 mM
  • 使用に関する注意

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • 由来

    Synthetic

  • 研究分野

    Ketotifen fumarate (ab120782) 使用論文

    This product has been referenced in:
    • Monument MJ  et al. The mast cell stabilizer ketotifen fumarate lessens contracture severity and myofibroblast hyperplasia: a study of a rabbit model of posttraumatic joint contractures. J Bone Joint Surg Am 92:1468-77 (2010). Read more (PubMed: 20516323) »
    • Sánchez-Patán F  et al. Mast cell inhibition by ketotifen reduces splanchnic inflammatory response in a portal hypertension model in rats. Exp Toxicol Pathol 60:347-55 (2008). Read more (PubMed: 18514499) »
    • Yamada Y  et al. Effect of ketotifen on the production of reactive oxygen species from human eosinophils primed by eotaxin. Pharmacology 69:138-41 (2003). Read more (PubMed: 14512700) »
    • Greenwood C The pharmacology of ketotifen. Chest 82:45S-48S (1982). Read more (PubMed: 6123414) »

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"