製品の概要

  • 製品名
    Ketoconazole
  • 製品の詳細
    Potent cytochrome P450 inhibitor. Antifungal agent.
  • 生理活性の詳細
    Potent cytochrome P450 inhibitor (Ki values are 26.7 and 109 nM at CYP3A4 and CYP3A5, respectively). Antifungal agent. Additionally, shows activity at human androgen receptors.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Shah SS  et al. Inhibitory effects of ketoconazole, cimetidine and erythromycin on hepatic CYP3A activities in cats. J Vet Med Sci 71:1151-9 (2009). Read more (PubMed: 19801894) »
  • Gibbs MA  et al. Inhibition of cytochrome P-450 3A (CYP3A) in human intestinal and liver microsomes: comparison of Ki values and impact of CYP3A5 expression. Drug Metab Dispos 27:180-7 (1999). Read more (PubMed: 9929500) »
  • Eil C Ketoconazole binds to the human androgen receptor. Horm Metab Res 24:367-70 (1992). Read more (PubMed: 1526623) »

See 0 Publications for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab120620.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

登録