製品の概要

  • 製品名Anti-Keratin 12 antibody
    Keratin 12 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Keratin 12
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    KLH conjugated synthetic peptide from a region between amino acids 449-479 from the C-terminal region of Human Keratin 12 (NP_000214.1).

  • ポジティブ・コントロール
    • K562 cell line lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab113039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 54 kDa.

ターゲット情報

  • 機能May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity.
  • 組織特異性Cornea specific.
  • 関連疾患Defects in KRT12 are a cause of Meesmann corneal dystrophy (MECD) [MIM:122100]; also abbreviated MCD and known as juvenile epithelial corneal dystrophy of Meesmann. MECD is an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Patients are usually asymptomatic until adulthood when rupture of the corneal microcysts may cause erosions, producing clinical symptoms such as photophobia, contact lens intolerance and intermittent diminution of visual acuity. Rarely, subepithelial scarring causes irregular corneal astigmatism and permanent visual impairment. Histological examination shows a disorganized and thickened epithelium with widespread cytoplasmic vacuolation and numerous small, round, debris-laden intraepithelial cysts.
  • 配列類似性Belongs to the intermediate filament family.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CK-12 antibody
    • Cytokeratin-12 antibody
    • K12 antibody
    • K1C12_HUMAN antibody
    • Keratin 12 antibody
    • Keratin antibody
    • Keratin, type I cytoskeletal 12 antibody
    • Keratin-12 antibody
    • KRT12 antibody
    • type I cytoskeletal 12 antibody
    see all

Anti-Keratin 12 antibody 画像

  • Anti-Keratin 12 antibody (ab113039) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 54 kDa

Anti-Keratin 12 antibody (ab113039) 使用論文

ab113039 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113039.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"