Anti-KDM5A / Jarid1A / RBBP2 抗体 (ab92533)

製品の概要

  • 製品名Anti-KDM5A / Jarid1A / RBBP2 antibody
    KDM5A / Jarid1A / RBBP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KDM5A / Jarid1A / RBBP2
  • アプリケーション適用あり: IHC-P, ICCmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Rabbit, Horse, Guinea pig, Dog, Gorilla, Chinese Hamster, Orangutan
  • 免疫原

    Synthetic peptide corresponding to Human KDM5A/ Jarid1A/ RBBP2 aa 1640-1690.

  • ポジティブ・コントロール
    • Human prostate carcinoma.
  • 特記事項

    Concentration is optimized for IHC and not determined

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab92533 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/100 - 1/500.
ICC 1/50 - 1/500.

ターゲット情報

  • 機能Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12.
  • 配列類似性Belongs to the JARID1 histone demethylase family.
    Contains 1 ARID domain.
    Contains 1 JmjC domain.
    Contains 1 JmjN domain.
    Contains 3 PHD-type zinc fingers.
  • ドメインThe GSGFP motif is required for the interaction with SUZ12.
  • 細胞内局在Nucleus > nucleolus. Occupies promoters of genes involved in RNA metabolism and mitochondrial function.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Histone demethylase JARID1A antibody
    • JARID1A antibody
    • Jumonji/ARID domain containing protein 1A antibody
    • Jumonji/ARID domain-containing protein 1A antibody
    • Kdm5a antibody
    • KDM5A_HUMAN antibody
    • Lysine-specific demethylase 5A antibody
    • RBBP-2 antibody
    • RBBP2 antibody
    • RBP2 antibody
    • Retinoblastoma binding protein 2 antibody
    • Retinoblastoma-binding protein 2 antibody
    see all

Anti-KDM5A / Jarid1A / RBBP2 antibody 画像

  • ab92533 at 1/250 dilution staining KDM5A / Jarid1A / RBBP2 in human prostate carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue. Detection: DAB staining.
  • Immunohistochemical analysis of parafin embedded human breast carcinoma tissue labelling KDM5A/Jarid1A/RBBP2 with ab92533 at 1 in 250 dilution.

Anti-KDM5A / Jarid1A / RBBP2 antibody (ab92533) 使用論文

ab92533 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"