製品の概要

  • 製品名Anti-KDM4B / JMJD2B antibody
    KDM4B / JMJD2B 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KDM4B / JMJD2B
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 10-40 of Human KDM4B/ JMJD2B

  • ポジティブ・コントロール
    • K562 cell lysate, Human Testis tissue

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab103129 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 122 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

ターゲット情報

  • 機能Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
  • 配列類似性Belongs to the JHDM3 histone demethylase family.
    Contains 1 JmjC domain.
    Contains 1 JmjN domain.
    Contains 2 PHD-type zinc fingers.
    Contains 2 Tudor domains.
  • ドメインThe 2 Tudor domains recognize and bind methylated histones. Double Tudor domain has an interdigitated structure and the unusual fold is required for its ability to bind methylated histone tails.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • JHDM3B antibody
    • JmjC domain-containing histone demethylation protein 3B antibody
    • JMJD2B antibody
    • Jumonji domain containing protein 2B antibody
    • Jumonji domain-containing protein 2B antibody
    • Kdm4b antibody
    • KDM4B_HUMAN antibody
    • KIAA0876 antibody
    • Lysine-specific demethylase 4B antibody
    see all

Anti-KDM4B / JMJD2B antibody 画像

  • Anti-KDM4B / JMJD2B antibody (ab103129) at 1/100 dilution + K562 cell lysate at 35 µg

    Predicted band size : 122 kDa
  • Formalin-fixed and paraffin-embedded Human Testis tissue, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining, using ab103129 at a dilution of 1/50.

Anti-KDM4B / JMJD2B antibody (ab103129) 使用論文

ab103129 has not yet been referenced specifically in any publications.

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