製品の概要

  • 製品名Anti-KDEL Receptor antibody [2E7]
    KDEL Receptor 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2E7] to KDEL Receptor
  • アプリケーション適用あり: IHC-P, WB, ICC/IFmore details
  • 種交差性
    交差種: Drosophila melanogaster, Plants, Wheat, Other
  • 免疫原

    synthetic peptide corresponding to the C-terminus of Saccharomyces cerevisiae KDEL receptor.

  • ポジティブ・コントロール
    • Saccharomyces cerevisiae lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名2E7
  • アイソタイプIgG2b
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab96720 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
WB 1/1000 - 1/2000. Predicted molecular weight: 78 kDa.
ICC/IF 1/50 - 1/100.

ターゲット情報

  • 関連性Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product.
  • 細胞内局在Endoplasmic reticulum
  • 別名
    • ER lumen protein retaining receptor 1 antibody
    • ERD 2 antibody
    • ERD2 antibody
    • ERD2.1 antibody
    • ERD21 antibody
    • HDEL antibody
    • KDEL (Lys Asp Glu Leu) endoplasmic reticulum protein retention receptor 1 antibody
    • KDEL (Lys-Asp-Glu-Leu) 72 kD endoplasmic reticulum protein retention receptor 1 antibody
    • KDEL endoplasmic reticulum protein retention receptor 1 antibody
    • KDEL R1 antibody
    • KDEL receptor 1 antibody
    • KDELR 1 antibody
    • KDELR1 antibody
    • PM 23 antibody
    • PM23 antibody
    • Putative MAPK activating protein PM23 antibody
    see all

Anti-KDEL Receptor antibody [2E7] 画像

  • ab96720 at 1/20,000 dilution staining KDEL Receptor in a Human kidney tissue section by Immunohistochemistry (Formalin/PFA fixed paraffin-embedded sections). Secondary antibody was biotinylated Goat anti-mouse. Picture at 400X magnification.

Anti-KDEL Receptor antibody [2E7] (ab96720) 使用論文

ab96720 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"