Anti-KDEL 抗体 [10C3] (Phycoerythrin) (ab115636)

製品の概要

  • 製品名Anti-KDEL antibody [10C3] (Phycoerythrin)
    KDEL 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [10C3] to KDEL (Phycoerythrin)
  • 標識Phycoerythrin. Ex: 488nm, Em: 575nm
  • 特異性ab115636 cross reacts with proteins containing the KDEL sequence.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性

    交差が予測される動物種: Bird, Plants, all Mammals
  • 免疫原

    Synthetic peptide:

    SEKDEL

    , corresponding to amino acids 649-654 of Rat KDEL.

  • ポジティブ・コントロール
    • Jurkat cells.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名10C3
  • アイソタイプIgG2a
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab115636 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt 1/100.

ターゲット情報

  • 関連性The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.
  • 細胞内局在Endoplasmic reticulum
  • 別名
    • KDEL antibody
    • Lys Asp Glu Leu antibody

Anti-KDEL antibody [10C3] (Phycoerythrin) 画像

  • ab115636 at 10µg/ml staining KDEL in 106 Jurkat cells by Flow cytometry (shown in red).
    Grey: unstained;Yellow: isotype control.

Anti-KDEL antibody [10C3] (Phycoerythrin) (ab115636) 使用論文

ab115636 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"