製品の概要

  • 製品名Anti-KCTD11 antibody
    KCTD11 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KCTD11
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    A region within synthetic peptide: ILNFLRLGRL DLPRGYGETA LLRAEADFYQ IRPLLDALRE LEASQGTPAP, corresponding to N terminal amino acids 36-85 of Human KCTD11

  • ポジティブ・コントロール
    • HepG2 cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab33059 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 26 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA 1/62500.

ターゲット情報

  • 関連性The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor promoting Hedgehog pathway in medulloblastoma. Plays a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state.
  • 参照データベース
  • 別名
    • C 17 orf 36 antibody
    • C17orf36 antibody
    • MGC 129844 antibody
    • Potassium channel tetramerisation domain containing 11 antibody
    • REN antibody
    • Retinoic acid EGF NGF induced gene protein antibody
    see all

Anti-KCTD11 antibody 画像

  • Anti-KCTD11 antibody (ab33059) at 1.25 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti Rabbit IgG at 1/50000 dilution

    Predicted band size : 26 kDa
    Observed band size : 26 kDa

Anti-KCTD11 antibody (ab33059) 使用論文

ab33059 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab33059.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"