製品の概要

  • 製品名Anti-KCNV2 antibody
    KCNV2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KCNV2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide corresponding to a region from N terminal amino acids 36-85 (

    RSGSQASIHGWTEGNYNYYIEEDEDGEEEDQWKDDLAEEDQQAGEVTTAK

    ) of Human KCNV2 (NP_598004).

  • ポジティブ・コントロール
    • 293T Cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab85595 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 62 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
  • 組織特異性Detected in lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary and colon.
  • 関連疾患Defects in KCNV2 are the cause of cone dystrophy retinal type 3B (RCD3B) [MIM:610356]; also called cone dystrophy with night blindness and supernormal rod responses KCNV2-related. RCD3B is a rare form of cone dystrophy associated with supernormal rod responses. The disorder is characterized by reduced visual acuity, photoaversion, night blindness, and abnormal color vision. At an early age, the retina shows subtle depigmentation at the macula and, later, more obvious areas of atrophy.
  • 配列類似性Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.2/KCNV2 sub-subfamily.
  • ドメインThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 細胞内局在Cell membrane. Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KCNV2 antibody
    • KCNV2_HUMAN antibody
    • KV11.1 antibody
    • Kv8.2 antibody
    • MGC120515 antibody
    • Potassium channel subfamily V member 2 antibody
    • Potassium voltage-gated channel subfamily V member 2 antibody
    • RCD3B antibody
    • Voltage-gated potassium channel Kv8.2 antibody
    • Voltage-gated potassium channel subunit Kv8.2 antibody
    see all

Anti-KCNV2 antibody 画像

  • Anti-KCNV2 antibody (ab85595) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T Cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 62 kDa
    Observed band size : 62 kDa

Anti-KCNV2 antibody (ab85595) 使用論文

ab85595 has not yet been referenced specifically in any publications.

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