製品の概要

  • 製品名Anti-KCNV1 antibody
    KCNV1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KCNV1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 36-85 (ALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAV P) of human KCNV1 (NP_055194).

  • ポジティブ・コントロール
    • 293T cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified by peptide affinity chromatography method.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab85495 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 56 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.
  • 組織特異性Detected in brain.
  • 配列類似性Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
  • ドメインThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 細胞内局在Cell membrane. Has to be associated with another potassium channel subunit to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB2.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KCNV1 antibody
    • KCNV1_HUMAN antibody
    • Neuronal potassium channel alpha subunit HNKA antibody
    • Potassium voltage gated channel subfamily V member 1 antibody
    • Potassium voltage-gated channel subfamily V member 1 antibody
    • Voltage gated potassium channel subunit Kv8.1 antibody
    • Voltage-gated potassium channel subunit Kv8.1 antibody
    see all

Anti-KCNV1 antibody 画像

  • Anti-KCNV1 antibody (ab85495) at 1 µg/ml ( in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 56 kDa
    Observed band size : 56 kDa

Anti-KCNV1 antibody (ab85495) 使用論文

ab85495 has not yet been referenced specifically in any publications.

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