製品の概要

  • 製品名Anti-KCNQ3 antibody
    KCNQ3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KCNQ3
  • 特異性This antibody is specific for KCNQ3 and does not detect KCNQ1, KCNQ2, KCNQ4 or KCNQ5.
  • アプリケーション適用あり: ICC/IF, ICC, IHC-Frmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Recombinant fragment (proprietary-tag) corresponding to Rat KCNQ3 aa 1-71 (N terminal).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: PBS, 1mg/ml BSA
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab16228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF
ICC
IHC-Fr
  • 追加情報ICC: Use at a concentration of 0.5 µg/ml.
    IF: Use at a concentration of 0.5 µg/ml.
    IHC-Fr: Use at a concentration of 0.5 µg/ml. This antibody gives a strong signal mainly in interneurons and astrocytes in the dentate region of rat hippocampal samples.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.
    • 組織特異性Predominantly expressed in brain.
    • 関連疾患Defects in KCNQ3 are the cause of benign neonatal epilepsy type 2 (EBN2) [MIM:121201]. Benign neonatal epilepsy is characterized by clusters of seizures occurring in the first days of life. Most patients have spontaneous remission by 12 months of age and show normal psychomotor development. The disorder is distinguished from benign familial infantile seizures by an earlier age at onset.
    • 配列類似性Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.3/KCNQ3 sub-subfamily.
    • ドメインThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BFNC 2 antibody
      • BFNC antibody
      • BFNC2 antibody
      • EBN 2 antibody
      • EBN2 antibody
      • KCNQ 3 antibody
      • KCNQ3 antibody
      • KCNQ3_HUMAN antibody
      • KQT like 3 antibody
      • KQT-like 3 antibody
      • KV7.3 antibody
      • Potassium channel subunit alpha KvLQT3 antibody
      • Potassium channel voltage gated subfamily Q member 3 antibody
      • Potassium voltage gated channel KQT like protein 3 antibody
      • Potassium voltage gated channel KQT like subfamily member 3 antibody
      • Potassium voltage gated channel subfamily KQT member 3 antibody
      • Potassium voltage-gated channel subfamily KQT member 3 antibody
      • Voltage gated potassium channel subunit Kv7.3 antibody
      • Voltage-gated potassium channel subunit Kv7.3 antibody
      see all

    Anti-KCNQ3 antibody (ab16228) 使用論文

    ab16228 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab16228.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"