製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to KCNK3
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Sheep, Cow, Dog
  • 免疫原

    A region within synthetic peptide: IPMIIPRDLS TSDTCVEQSH SSPGGGGRYS DTPSRRCLCS GAPRSAISSV, corresponding to C terminal amino acids 325-374 of Human KCNK3

  • ポジティブ・コントロール
    • Jurkat cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度
    Protein A purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab49433 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 43 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA: titre using peptide based assay: 1/1562500.

ターゲット情報

  • 機能
    pH-dependent, voltage-insensitive, background potassium channel protein. Rectification direction results from potassium ion concentration on either side of the membrane. Acts as an outward rectifier when external potassium concentration is low. When external potassium concentration is high, current is inward.
  • 組織特異性
    Widespread expression in adult. Strongest expression in pancreas and placenta. Lower expression in brain, lung, prostate, heart, kidney, uterus, small intestine and colon.
  • 関連疾患
    Pulmonary hypertension, primary, 4
  • 配列類似性
    Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
  • 細胞内局在
    Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Acid sensitive potassium channel protein TASK 1 antibody
    • Acid sensitive potassium channel protein TASK antibody
    • Acid-sensitive potassium channel protein TASK-1 antibody
    • Cardiac two pore background K(+) channel antibody
    • cTBAK 1 antibody
    • K2p3.1 antibody
    • KCNK3 antibody
    • KCNK3_HUMAN antibody
    • OAT1 antibody
    • Potassium channel subfamily K member 3 antibody
    • potassium channel, subfamily K, member 3 antibody
    • Potassium inwardly rectifying channel subfamily K member 3 antibody
    • PPH4 antibody
    • rTASK antibody
    • TASK 1 antibody
    • TASK antibody
    • TBAK1 antibody
    • TWIK related acid sensitive K+ channel antibody
    • TWIK-related acid-sensitive K(+) channel 1 antibody
    • Two P domain potassium channel antibody
    • Two pore K(+) channel KT3. antibody
    • Two pore K(+) channel KT3.1 antibody
    • Two pore potassium channel KT3.1 antibody
    see all

Anti-KCNK3 antibody 画像

  • Anti-KCNK3 antibody (ab49433) at 1.25 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 43 kDa
    Observed band size : 38 kDa (why is the actual band size different from the predicted?)

プロトコール

Anti-KCNK3 antibody (ab49433) 使用論文

ab49433 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab49433.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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