製品の概要

  • 製品名Anti-KCNIP1 antibody
    KCNIP1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KCNIP1
  • アプリケーション適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide: MGAVMGTFSS LQTKQRRPSK DKIEDELEMT MVCHRPEGLE QLEAQTNFTK, corresponding to a region within N terminal amino acids 1-50 of Human KCNIP1

  • ポジティブ・コントロール
    • Jurkat cells. Brain.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Protein A purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab66628 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay 1:312500.

WB Use a concentration of 1.35 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 24 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.

ターゲット情報

  • 機能Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.
  • 組織特異性Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus.
  • 配列類似性Belongs to the recoverin family.
    Contains 4 EF-hand domains.
  • 細胞内局在Cell membrane. Cytoplasm. Cell projection, dendrite.
  • Information by UniProt
  • 参照データベース
  • 製品の状態There are 3 isoforms produced by alternative splicing.
  • 別名
    • A type potassium channel modulatory protein 1 antibody
    • A-type potassium channel modulatory protein 1 antibody
    • KChIP1 antibody
    • KCIP1_HUMAN antibody
    • Kcnip1 antibody
    • Kv channel interacting protein 1 antibody
    • Kv channel-interacting protein 1 antibody
    • MGC9 antibody
    • MGC95 antibody
    • Potassium channel interacting protein 1 antibody
    • Potassium channel-interacting protein 1 antibody
    • VABP antibody
    • Vesicle APC binding protein antibody
    • Vesicle APC-binding protein antibody
    see all

Anti-KCNIP1 antibody 画像

  • Anti-KCNIP1 antibody (ab66628) at 1.35 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 24 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 70 kDa. We are unsure as to the identity of these extra bands.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human brain tissue labelling KCNIP1 with ab66628 at 4-8µg/ml. Arrows indicate positively labelled neural cells. Magnification: 400X.

Anti-KCNIP1 antibody (ab66628) 使用論文

ab66628 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab66628.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"