製品の概要

  • 製品名
    Anti-KCNC1 antibody [N16B/8]
    KCNC1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [N16B/8] to KCNC1
  • 特異性
    Weak cross reactivity with human.
  • アプリケーション
    適用あり: IHC-Fr, IHC-P, WB, ICC/IFmore details
  • 種交差性
    交差種: Mouse, Rat
  • 免疫原

    Fusion protein, corresponding to cytoplasmic C terminal amino acids 437-585 of Rat KCNC1 (NP_036988).

  • ポジティブ・コントロール
    • Rat brain lysate.
  • 特記事項

    The clone number has been updated from S16B-8 to N16B/8, both clone numbers name the same antibody clone.

     

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: 50% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • 精製度
    Protein G purified
  • ポリ/モノ
    モノクローナル
  • クローン名
    N16B/8
  • アイソタイプ
    IgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab84823 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-Fr Use a concentration of 0.1 - 1 µg/ml.
IHC-P Use a concentration of 0.1 - 1 µg/ml.
WB Use a concentration of 1 - 10 µg/ml. Predicted molecular weight: 58 kDa.
ICC/IF Use a concentration of 1 - 10 µg/ml.

ターゲット情報

  • 機能
    Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons.
  • 関連疾患
    Epilepsy, progressive myoclonic 7
  • 配列類似性
    Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily.
  • ドメイン
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
    The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C230009H10Rik antibody
    • FLJ41162 antibody
    • FLJ42249 antibody
    • FLJ43491 antibody
    • Kcnc1 antibody
    • KCNC1_HUMAN antibody
    • Kcr2 1 antibody
    • KShIIIB antibody
    • Kv3.1 antibody
    • Kv4 antibody
    • MGC129855 antibody
    • NGK2 antibody
    • Potassium voltage-gated channel subfamily C member 1 antibody
    • Shaw antibody
    • Voltage gated potassium channel antibody
    • Voltage gated potassium channel subunit Kv3.1 antibody
    • Voltage-gated potassium channel subunit Kv3.1 antibody
    • Voltage-gated potassium channel subunit Kv4 antibody
    see all

画像

  • All lanes : Anti-KCNC1 antibody [N16B/8] (ab84823) at 1 µg/ml

    Lane 1 : Molecular weight marker
    Lane 2 : Tissue lysates prepared from rat brain


    Predicted band size : 58 kDa

参考文献

This product has been referenced in:
  • Uchino K  et al. Therapeutic Effects of MicroRNA-582-5p and -3p on the Inhibition of Bladder Cancer Progression. Mol Ther 21:610-9 (2013). Read more (PubMed: 23295946) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab84823.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録