製品の概要

  • 製品名Anti-KCNC1 antibody
    KCNC1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KCNC1
  • アプリケーション適用あり: WB, IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from C terminal domain of human KCNC1.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: Whole serum
  • 精製度Whole antiserum
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab66619 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/5000. Predicted molecular weight: 58 kDa.
IHC-P Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

ターゲット情報

  • 機能Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well. Contributes to fire sustained trains of very brief action potentials at high frequency in pallidal neurons.
  • 関連疾患Epilepsy, progressive myoclonic 7
  • 配列類似性Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily.
  • ドメインThe segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
    The tail may be important in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C230009H10Rik antibody
    • FLJ41162 antibody
    • FLJ42249 antibody
    • FLJ43491 antibody
    • Kcnc1 antibody
    • KCNC1_HUMAN antibody
    • Kcr2 1 antibody
    • KShIIIB antibody
    • Kv3.1 antibody
    • Kv4 antibody
    • MGC129855 antibody
    • NGK2 antibody
    • Potassium voltage-gated channel subfamily C member 1 antibody
    • Shaw antibody
    • Voltage gated potassium channel antibody
    • Voltage gated potassium channel subunit Kv3.1 antibody
    • Voltage-gated potassium channel subunit Kv3.1 antibody
    • Voltage-gated potassium channel subunit Kv4 antibody
    see all

Anti-KCNC1 antibody (ab66619) 使用論文

ab66619 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Mouse Tissue sections (Spinal Cord slices)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Sodium Citrate
Permeabilization Yes - Triton 0.3%
Specification Spinal Cord slices
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 20°C
Fixative Paraformaldehyde
Username

Mr. Pierce Mullen

Verified customer

投稿 Nov 25 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"