製品の概要

  • 製品名Anti-KCNA3 (phospho Y135) antibody
    KCNA3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KCNA3 (phospho Y135)
  • 特異性ab61105 detects endogenous levels of KCNA3 only when phosphorylated at tyrosine 135.
  • アプリケーション適用あり: ICC/IF, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic phosphopeptide derived from human KCNA3 around the phosphorylation site of tyrosine 135 (R-F-YP-Q-L).

  • ポジティブ・コントロール
    • HuvEc cells

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS, 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab61105 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/100 - 1/500.
ELISA 1/20000.

ターゲット情報

  • 機能Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.
  • 配列類似性Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.3/KCNA3 sub-subfamily.
  • ドメインThe N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments.
    The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position.
  • 細胞内局在Membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • HGK 5 antibody
    • HGK5 antibody
    • HLK 3 antibody
    • HLK3 antibody
    • HPCN 3 antibody
    • HPCN3 antibody
    • HuKIII antibody
    • KCNA 3 antibody
    • Kcna3 antibody
    • KCNA3_HUMAN antibody
    • KV1.3 antibody
    • MK 3 antibody
    • MK3 antibody
    • OTTHUMP00000032397 antibody
    • PCN 3 antibody
    • PCN3 antibody
    • Potassium channel 3 antibody
    • Potassium voltage gated channel shaker related subfamily member 3 antibody
    • Potassium voltage gated channel subfamily A member 3 antibody
    • Potassium voltage-gated channel subfamily A member 3 antibody
    • Type n potassium channel antibody
    • Voltage gated potassium channel protein Kv1.3 antibody
    • Voltage gated potassium channel subunit Kv1.3 antibody
    • Voltage-gated K(+) channel HuKIII antibody
    • Voltage-gated potassium channel subunit Kv1.3 antibody
    see all

Anti-KCNA3 (phospho Y135) antibody 画像

  • Immunofluorescent staining of HuvEc cells, using ab61105 at a 1/100 dilution, minus immunising peptide (left image) and plus immunising peptide (right image).

Anti-KCNA3 (phospho Y135) antibody (ab61105) 使用論文

ab61105 has not yet been referenced specifically in any publications.

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