製品の概要

  • 製品名Anti-KChIP2 antibody
    KChIP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KChIP2
  • アプリケーション適用あり: ELISA, WB, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • 免疫原

    Synthetic peptide derived from residues 22 - 71 of human KCNIP2.

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  • ポジティブ・コントロール
    • Jurkat cell lysate.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab28734 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/62500.
WB Use a concentration of 0.06 µg/ml. Detects a band of approximately 24 kDa (predicted molecular weight: 31 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use at an assay dependent concentration.

ターゲット情報

  • 機能Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND2/Kv4.2 and KCND3/Kv4.3 currents. Involved in KCND2 and KCND3 trafficking to the cell surface. May be required for the expression of I(To) currents in the heart.
  • 組織特異性Expressed in brain. Colocalizes with KCND2 in excitatory neurons including cortical and hippocampal CA1 pyramidal cells. Isoform 3 is expressed in heart and in umbilical vein endothelial cells. Not expressed in fetal heart.
  • 配列類似性Belongs to the recoverin family.
    Contains 4 EF-hand domains.
  • 翻訳後修飾Palmitoylated. Palmitoylation enhances association with the plasma membrane.
  • 細胞内局在Cell membrane and Cell membrane. Detected on lipid rafts (By similarity).
  • Information by UniProt
  • 参照データベース
  • 製品の状態There are 9 isoforms produced by alternative splicing.
  • 別名
    • A type potassium channel modulatory protein 2 antibody
    • A-type potassium channel modulatory protein 2 antibody
    • Cardiac voltage gated potassium channel modulatory subunit antibody
    • Cardiac voltage-gated potassium channel modulatory subunit antibody
    • DKFZp566L1246 antibody
    • KChIP 2 antibody
    • KChIP2 antibody
    • KCIP2_HUMAN antibody
    • KCNIP 2 antibody
    • Kcnip2 antibody
    • Kv channel interacting protein 2 antibody
    • Kv channel-interacting protein 2 antibody
    • MGC17241 antibody
    • Potassium channel interacting protein 2 antibody
    • Potassium channel-interacting protein 2 antibody
    see all

Anti-KChIP2 antibody 画像

  • Anti-KChIP2 antibody (ab28734) at 0.06 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti rabbit IgG at 1/50000 dilution

    Predicted band size : 31 kDa
    Observed band size : 24 kDa (why is the actual band size different from the predicted?)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human brain tissue labelling KChIP2 with ab28734 at 4-8µg/ml. Cells with positive labelling (indicated with arrows) are neural cells. Magnification: 400X.

Anti-KChIP2 antibody (ab28734) 使用論文

ab28734 has not yet been referenced specifically in any publications.

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