製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to KCC4
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rabbit
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 845-1056 of Human KCC4 (NP_006589).

  • ポジティブ・コントロール
    • A431, H1299, HepG2 and Raji whole cell lysates

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96424 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 119 kDa.

ターゲット情報

  • 機能
    Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.
  • 組織特異性
    Detected in muscle, brain, lung, heart and kidney.
  • 配列類似性
    Belongs to the SLC12A transporter family.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • D13Ertd261e antibody
    • Electroneutral potassium-chloride cotransporter 4 antibody
    • Furosemide sensitive KCl cotransporter 4 antibody
    • K Cl cotransporter KCC4 antibody
    • K-Cl cotransporter 4 antibody
    • Potassium/chloride transporter KCC4 antibody
    • S12A7_HUMAN antibody
    • SLC12A7 antibody
    • Solute carrier family 12 (potassium/chloride transporters), member 7 antibody
    • Solute carrier family 12 member 7 antibody
    • Solute carrier family 12, member 7 antibody
    see all

画像

  • Anti-KCC4 antibody (ab96424) at 1/500 dilution + H1299 whole cell lysate at 30 µg

    Predicted band size : 119 kDa

プロトコール

参考文献

ab96424 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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