製品の概要

  • 製品名Anti-Kazrin antibody
    Kazrin 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to Kazrin
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat, Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-415 of Human Kazrin (NP_001018000.1)

  • ポジティブ・コントロール
    • Rat brain tissue lysate and transfected 293T cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab88752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 86 kDa.

ターゲット情報

  • 機能Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.
  • 組織特異性Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level).
  • 配列類似性Belongs to the kazrin family.
    Contains 3 SAM (sterile alpha motif) domains.
  • 細胞内局在Cytoplasm > cytoskeleton and Cytoplasm. Cell junction > desmosome. Nucleus. Observed at the apical plasma mebrane of keratinocytes. Partially colocalizes with PPL and DP at desmosomes, and with PP at the interdesmosomal plasma membrane. Colocalizes with cortical actin-based membrane structures.
  • Information by UniProt
  • 参照データベース
  • 別名
    • HRIHFB2003 antibody
    • KAZ antibody
    • Kazn antibody
    • Kazrin antibody
    • KAZRN_HUMAN antibody
    • KIAA1026 antibody
    • RP1-21O18.1 antibody
    see all

Anti-Kazrin antibody 画像

  • Anti-Kazrin antibody (ab88752) at 1 µg/ml + Rat brain tissue lysate at 50ug/lane

    Predicted band size : 86 kDa
    Observed band size : 86 kDa
    Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.
  • All lanes : Anti-Kazrin antibody (ab88752) at 1 µg/ml

    Lane 1 : Kazrin transfected 293T cell lysate (45.65 kDa) at 25ug/lane
    Lane 2 : Non-transfected 293T cell lysate at 25ug/lane


    Predicted band size : 86 kDa
    Observed band size : 60 kDa (why is the actual band size different from the predicted?)

Anti-Kazrin antibody (ab88752) 使用論文

ab88752 has not yet been referenced specifically in any publications.

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