製品の概要

  • 製品名Anti-KAT2B / PCAF antibody
    KAT2B / PCAF 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KAT2B / PCAF
  • アプリケーション適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide, corresponding to a region within the C terminal amino acids 767-832 of Human KAT2B/ PCAF.

  • ポジティブ・コントロール
    • 293T, A431, H1299, HeLa S3, HepG2, MOLT4, Raji cells, HeLa cell lysates

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96510 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 93 kDa.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
  • 組織特異性Ubiquitously expressed but most abundant in heart and skeletal muscle.
  • 配列類似性Belongs to the GCN5 family.
    Contains 1 bromo domain.
    Contains 1 N-acetyltransferase domain.
  • ドメインThe bromodomain mediates binding to HIV-1 Tat.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CAF antibody
    • CREBBP associated factor antibody
    • GCN5 antibody
    • GCN5L antibody
    • GCN5L1 antibody
    • Histone acetylase PCAF antibody
    • Histone acetyltransferase KAT2B antibody
    • Histone acetyltransferase PCAF antibody
    • K(lysine) acetyltransferase 2B antibody
    • KAT2B antibody
    • KAT2B_HUMAN antibody
    • Lysine acetyltransferase 2B antibody
    • P antibody
    • P/CAF antibody
    • p300/CBP associated factor antibody
    • P300/CBP-associated factor antibody
    • Pcaf antibody
    see all

Anti-KAT2B / PCAF antibody 画像

  • Anti-KAT2B / PCAF antibody (ab96510) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 93 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed HeLa cells, using ab96510 at 1:200 dilution. Image 2: Merged with DNA probe.

Anti-KAT2B / PCAF antibody (ab96510) 使用論文

ab96510 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"