製品の概要

  • 製品名Anti-KAT2B / PCAF antibody
    KAT2B / PCAF 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to KAT2B / PCAF
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: LEEEVYSQNS PIWDQDFLSA SSRTSQLGIQ TVINPPPVAG TISYNSTSSS LEQPNAGSSS PACKASSGLE ANPGEKRKMT DSHVLEEAKK PRVMGDIPME , corresponding to amino acids 353-452 of Human PCAF

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56535 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes.
    • 組織特異性Ubiquitously expressed but most abundant in heart and skeletal muscle.
    • 配列類似性Belongs to the GCN5 family.
      Contains 1 bromo domain.
      Contains 1 N-acetyltransferase domain.
    • ドメインThe bromodomain mediates binding to HIV-1 Tat.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • CAF antibody
      • CREBBP associated factor antibody
      • GCN5 antibody
      • GCN5L antibody
      • GCN5L1 antibody
      • Histone acetylase PCAF antibody
      • Histone acetyltransferase KAT2B antibody
      • Histone acetyltransferase PCAF antibody
      • K(lysine) acetyltransferase 2B antibody
      • KAT2B antibody
      • KAT2B_HUMAN antibody
      • Lysine acetyltransferase 2B antibody
      • P antibody
      • P/CAF antibody
      • p300/CBP associated factor antibody
      • P300/CBP-associated factor antibody
      • Pcaf antibody
      see all

    Anti-KAT2B / PCAF antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab56535 PCAF antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-KAT2B / PCAF antibody (ab56535) 使用論文

    ab56535 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab56535.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"