製品の概要

  • 製品名Anti-KAT1 / HAT1 antibody
    KAT1 / HAT1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KAT1 / HAT1
  • 特異性ab61225 detects endogenous levels of total HAT protein
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat
  • 免疫原

    Synthetic peptide derived from an internal region of human HAT1.

  • ポジティブ・コントロール
    • Extracts from LOVO cells

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab61225 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/5000.
WB 1/500 - 1/1000. Detects a band of approximately 49 kDa (predicted molecular weight: 49 kDa).

ターゲット情報

  • 機能Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.
  • 配列類似性Belongs to the HAT1 family.
  • 発生段階Highly expressed in mitotic cells (at protein level).
  • 細胞内局在Nucleus matrix and Cytoplasm. Nucleus. Nucleus matrix. Nucleus > nucleoplasm. Localization is predominantly nuclear in normal cells. Treatment with hydrogen peroxide or ionizing radiation enhances nuclear localization through redistribution of existing protein.
  • Information by UniProt
  • 参照データベース
  • 別名
    • HAT 1 antibody
    • hat1 antibody
    • HAT1_HUMAN antibody
    • Histidine aminotransferase 1 antibody
    • Histone acetyltransferase 1 antibody
    • Histone acetyltransferase 1 antibody
    • Histone acetyltransferase type B catalytic subunit antibody
    • KAT1 antibody
    see all

Anti-KAT1 / HAT1 antibody 画像

  • All lanes : Anti-KAT1 / HAT1 antibody (ab61225) at 1/500 dilution

    Lane 1 : extracts from LOVO cells
    Lane 2 : extracts from LOVO cells with immunizing peptide


    Predicted band size : 49 kDa
    Observed band size : 49 kDa

Anti-KAT1 / HAT1 antibody (ab61225) 使用論文

This product has been referenced in:
  • Zhou X  et al. Hepatic FoxO1 acetylation is involved in oleanolic acid-induced memory of glycemic control: novel findings from Study 2. PLoS One 9:e107231 (2014). WB ; Mouse . Read more (PubMed: 25222566) »
  • Ejlassi-Lassallette A  et al. H4 replication-dependent diacetylation and Hat1 promote S-phase chromatin assembly in vivo. Mol Biol Cell 22:245-55 (2011). WB ; Other . Read more (PubMed: 21118997) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"