製品の概要

  • 製品名Anti-KAT1 / HAT1 antibody
    KAT1 / HAT1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to KAT1 / HAT1
  • 特異性ab12163 specifically recognizes human HAT1.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Chicken, Human
  • 免疫原

    Synthetic peptide:

    EESFQELVEDYRRVIERLAQE

    with N-terminal added lysine conjugated to KLH, corresponding to amino acids 399-419 of Human HAT1. The corresponding sequence differs by three amino acids in chicken and by one amino acid in mouse (putative sequence).

  • ポジティブ・コントロール
    • Whole extracts of human 293 cells, mouse NIH-3T3 cells, or chicken fibroblasts.
  • 特記事項Storage in frost-free freezers is also not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab12163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/2500. Detects a band of approximately 46 kDa.

ターゲット情報

  • 機能Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.
  • 配列類似性Belongs to the HAT1 family.
  • 発生段階Highly expressed in mitotic cells (at protein level).
  • 細胞内局在Nucleus matrix and Cytoplasm. Nucleus. Nucleus matrix. Nucleus > nucleoplasm. Localization is predominantly nuclear in normal cells. Treatment with hydrogen peroxide or ionizing radiation enhances nuclear localization through redistribution of existing protein.
  • Information by UniProt
  • 参照データベース
  • 別名
    • HAT 1 antibody
    • hat1 antibody
    • HAT1_HUMAN antibody
    • Histidine aminotransferase 1 antibody
    • Histone acetyltransferase 1 antibody
    • Histone acetyltransferase 1 antibody
    • Histone acetyltransferase type B catalytic subunit antibody
    • KAT1 antibody
    see all

Anti-KAT1 / HAT1 antibody (ab12163) 使用論文

ab12163 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab12163.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"