Anti-Kappa light chain 抗体 [L1C1] (ab49646)


  • 製品名Anti-Kappa light chain antibody [L1C1]
    Kappa light chain 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [L1C1] to Kappa light chain
  • 特異性This antibody is specific to Kappa immunoglobulin light chain.
  • アプリケーション適用あり: IHC-Fr, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    B lymphoma cells.

  • ポジティブ・コントロール
    • Immunohistochemistry: Tonsil.


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 15mM Sodium Azide
    Constituents: Tissue culture supernatant
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名L1C1
  • ミエローマSp2/0
  • アイソタイプIgG1
  • 研究分野


Our Abpromise guarantee covers the use of ab49646 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報IHC-Fr: 1/20 - 1/40.
    IHC-P: 1/20 - 1/40. Trypsin digestion of paraffin sections is recommended.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
    • 細胞内局在Cytoplasmic and Secreted
    • 参照データベース
    • 別名
      • HCAK 1 antibody
      • HCAK1 antibody
      • Ig kappa chain C region antibody
      • IGKC antibody
      • IGKCD antibody
      • Immunoglobulin InV antibody
      • Immunoglobulin kappa constant antibody
      • Immunoglobulin kappa constant region antibody
      • Immunoglobulin kappa light chain antibody
      • Immunoglobulin kappa light chain constant region antibody
      • Immunoglobulin KM antibody
      • Kappa 1 immunoglobulin light chain antibody
      • kappa light chain antibody
      • Km antibody
      • MGC111575 antibody
      • MGC62011 antibody
      • MGC72072 antibody
      • MGC88770 antibody
      • MGC88771 antibody
      • MGC88809 antibody
      see all

    Anti-Kappa light chain antibody [L1C1] 画像

    • Ab49646, at a dilution of 1/20 staining kappa immunoglobulin light chains in paraffin section of normal human tonsil by immunohistochemistry. Note intense intracytoplasmic staining of plasma cells.

    Anti-Kappa light chain antibody [L1C1] (ab49646) 使用論文

    ab49646 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab49646.
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