Anti-Kappa light chain 抗体 [EPR5367-8] (ab124727)

製品の概要

  • 製品名Anti-Kappa light chain antibody [EPR5367-8]
    Kappa light chain 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR5367-8] to Kappa light chain
  • アプリケーション適用あり: WB, IP, ELISA, IHC-P, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Purified Human IgA.

  • ポジティブ・コントロール
    • WB: Human tonsil, plasma and spleen tissue lysates. IHC-P: Human tonsil tissue.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

     

    Alternative versions available:

    Anti-Kappa light chain antibody (Alexa Fluor® 647) [EPR5367-8] (ab202832)

    Anti-Kappa light chain antibody (HRP) [EPR5367-8] (ab202549)

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • 精製度Tissue culture supernatant
  • ポリ/モノモノクローナル
  • クローン名EPR5367-8
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab124727 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/10000 - 1/50000. Predicted molecular weight: 25 kDa.
IP 1/10 - 1/100.
ELISA 1/16000.
IHC-P 1/250 - 1/500. antigen retrieval is recommended.
ICC/IF 1/500 - 1/1000.

ターゲット情報

  • 関連性Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
  • 細胞内局在Cytoplasmic and Secreted
  • 参照データベース
  • 別名
    • HCAK 1 antibody
    • HCAK1 antibody
    • Ig kappa chain C region antibody
    • IGKC antibody
    • IGKCD antibody
    • Immunoglobulin InV antibody
    • Immunoglobulin kappa constant antibody
    • Immunoglobulin kappa constant region antibody
    • Immunoglobulin kappa light chain antibody
    • Immunoglobulin kappa light chain constant region antibody
    • Immunoglobulin KM antibody
    • Kappa 1 immunoglobulin light chain antibody
    • kappa light chain antibody
    • Km antibody
    • MGC111575 antibody
    • MGC62011 antibody
    • MGC72072 antibody
    • MGC88770 antibody
    • MGC88771 antibody
    • MGC88809 antibody
    see all

Anti-Kappa light chain antibody [EPR5367-8] 画像

  • All lanes : Anti-Kappa light chain antibody [EPR5367-8] (ab124727)

    Lane 1 : Human tonsil cell lysate
    Lane 2 : Human plasma cell lysate
    Lane 3 : Human spleen cell lysate

    Lysates/proteins at 10 µg per lane.


    Predicted band size : 25 kDa
  • Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using ab124727 at 1/250-500 dilution

Anti-Kappa light chain antibody [EPR5367-8] (ab124727) 使用論文

ab124727 has not yet been referenced specifically in any publications.

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Merci de nous avoir contactés.

Nous avons un anticorps semblable à l'anticorps A7164. C'est un monoclonal de lapin anti-Human IgG Kappa Light Chain, clone[EPR5367], référence ab124727, http://www.abcam.com/ab124727....

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"