Anti-Kappa light chain 抗体 (Biotin) (ab46807)

製品の概要

  • 製品名Anti-Kappa light chain antibody (Biotin)
    Kappa light chain 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Kappa light chain (Biotin)
  • 標識Biotin
  • 特異性Reacts with human kappa light chains as demonstrated by ELISA and flow cytometry. Cross Absorption: Pooled human myeloma proteins with kappa light chains and mouse immunoglobulins.
  • アプリケーション適用あり: Flow Cyt, ELISA, ICC/IF, WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Human myeloma proteins with kappa light chains

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Affinity chromatography on pooled human immunoglobulins with kappa light chains covalently linked to agarose.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab46807 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use 1µg for 106 cells. ab37376-Goat polyclonal IgG, is suitable for use as an isotype control with this antibody.
ELISA 1/5000 - 1/20000.
ICC/IF Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 12 kDa.
Dot blot Use at an assay dependent concentration.

ターゲット情報

  • 関連性Immunoglobulins belong to a group of related glyco proteins which make up 20% of serum proteins. Antigens and immunoglobulins react to confer immunity to individuals. Immunoglobulins have similar structures of two identical heavy chains and two identical light chains. Both the heavy chains and the light chains are divided into constant and variable regions. The constant regions have the same amino acid sequences between all the immunoglobulin classes. The variable regions have approximately 110 amino acids with high sequence variability. The amino acid sequence of the heavy chain determines the class of an immunoglobulin. The five types of immunoglobulin heavy chains are known as: IgG, IgA, IgM, IgD, and IgE. IgG is divided into four subclasses, and IgA is divided into two subclasses. In serum IgA and IgG are monomers with a single 4 polypeptide unit; while, IgM is a pen tamer. IgA may also form polymers. Kappa light chain antibody can be used for the identification of leukemias, plasmacytomas and certain non Hodgkin's lymphomas. Kappa light chain contains one immunoglobulin like domain. The EU sequence has the INV allotypic marker, Ala 45 and Val 83. The ROY sequence has the INV allotypic marker, Ala 45 and Leu 83.
  • 細胞内局在Cytoplasmic and Secreted
  • 参照データベース
  • 別名
    • HCAK 1 antibody
    • HCAK1 antibody
    • Ig kappa chain C region antibody
    • IGKC antibody
    • IGKCD antibody
    • Immunoglobulin InV antibody
    • Immunoglobulin kappa constant antibody
    • Immunoglobulin kappa constant region antibody
    • Immunoglobulin kappa light chain antibody
    • Immunoglobulin kappa light chain constant region antibody
    • Immunoglobulin KM antibody
    • Kappa 1 immunoglobulin light chain antibody
    • kappa light chain antibody
    • Km antibody
    • MGC111575 antibody
    • MGC62011 antibody
    • MGC72072 antibody
    • MGC88770 antibody
    • MGC88771 antibody
    • MGC88809 antibody
    see all

Anti-Kappa light chain antibody (Biotin) (ab46807) 使用論文

ab46807 has not yet been referenced specifically in any publications.

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