The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
追加情報WB: 1/500 - 1/1000.
In Western blot, this antibody is expected to detect a band of approximately 39 kDa, which corresponds to the predicted molecular weight of KLK L1.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
組織特異性Expressed in prostate.
関連疾患Defects in KLK4 are the cause of amelogenesis imperfecta hypomaturation type 2A1 (AI2A1) [MIM:204700]. AI2A1 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel.
配列類似性Belongs to the peptidase S1 family. Kallikrein subfamily. Contains 1 peptidase S1 domain.
Stephenson SA et al. Localization of a new prostate-specific antigen-related serine protease gene, KLK4, is evidence for an expanded human kallikrein gene family cluster on chromosome 19q13.3-13.4. J Biol Chem274:23210-4 (1999).
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