製品の概要

  • 製品名Anti-Kaiso antibody [EPR4668]
    Kaiso 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR4668] to Kaiso
  • アプリケーション適用あり: WBmore details
    適用なし: Flow Cyt,ICC,IHC-P or IP
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Kaiso (Human)

  • ポジティブ・コントロール
    • WB: Human heart, MCF7, C6, PC12 or NIH 3T3 lysates
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab124777 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 95 kDa (predicted molecular weight: 74 kDa).
  • 追加情報Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • ターゲット情報

    • 機能Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2.
    • 組織特異性Expressed in vascular endothelium.
    • 配列類似性Contains 1 BTB (POZ) domain.
      Contains 3 C2H2-type zinc fingers.
    • 細胞内局在Nucleus. Cytoplasm. Also cytoplasmic in cells grown at high densities.
    • Information by UniProt
    • 参照データベース
    • 別名
      • Kaiso antibody
      • Kaiso protein antibody
      • Kaiso transcription factor antibody
      • KAISO_HUMAN antibody
      • Transcriptional regulator Kaiso antibody
      • ZBTB 33 antibody
      • Zbtb33 antibody
      • Zinc finger and BTB domain containing 33 antibody
      • Zinc finger and BTB domain-containing protein 33 antibody
      • Zinc finger transcription factor Kaiso antibody
      • ZNF 348 antibody
      • ZNF Kaiso antibody
      • ZNF348 antibody
      see all

    Anti-Kaiso antibody [EPR4668] 画像

    • All lanes : Anti-Kaiso antibody [EPR4668] (ab124777) at 1/1000 dilution

      Lane 1 : Human heart lysate
      Lane 2 : MCF7 lysate
      Lane 3 : C6 lysate
      Lane 4 : PC12 lysate
      Lane 5 : NIH 3T3 lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      HRP labelled Goat anti Rabbit IgG at 1/2000 dilution

      Predicted band size : 74 kDa
      Observed band size : 95 kDa (why is the actual band size different from the predicted?)

    Anti-Kaiso antibody [EPR4668] (ab124777) 使用論文

    ab124777 has not yet been referenced specifically in any publications.

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"