Anti-KA1 抗体 (ab67404)
Key features and details
- Rabbit polyclonal to KA1
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-KA1 antibody
KA1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to KA1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat -
免疫原
A 14 amino acid peptide near the amino terminus of human KA1.
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ポジティブ・コントロール
- Rat brain lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab67404の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately <97 kDa (predicted molecular weight: 107 kDa).
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特記事項 |
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WB
Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately <97 kDa (predicted molecular weight: 107 kDa). |
ターゲット情報
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機能
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. -
配列類似性
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK4 subfamily. -
細胞内局在
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 24406 Rat
- SwissProt: Q01812 Rat
- Unigene: 10049 Rat
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別名
- EAA 1 antibody
- EAA1 antibody
- Excitatory amino acid receptor 1 antibody
see all
画像
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Lane 1 : Anti-KA1 antibody (ab67404) at 0.5 µg/ml
Lane 2 : Anti-KA1 antibody (ab67404) at 1 µg/ml
Lane 3 : Anti-KA1 antibody (ab67404) at 2 µg/ml
All lanes : rat brain lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 107 kDa
Observed band size: <97 kDa why is the actual band size different from the predicted?
Additional bands at: 108 kDa. We are unsure as to the identity of these extra bands.
N.B. Despite its predicted molecular weight, KA1 often migrates at a lower molecular weight in SDS-PAGE.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab67404 は 3 報の論文で使用されています。
- Ciarpella F et al. Murine cerebral organoids develop network of functional neurons and hippocampal brain region identity. iScience 24:103438 (2021). PubMed: 34901791
- Gu L et al. Erythropoietin exerts a neuroprotective function against glutamate neurotoxicity in experimental diabetic retina. Invest Ophthalmol Vis Sci 55:8208-22 (2014). PubMed: 25335981
- Marrocco J et al. Anxiety-like behavior of prenatally stressed rats is associated with a selective reduction of glutamate release in the ventral hippocampus. J Neurosci 32:17143-54 (2012). Rat . PubMed: 23197707