Anti-KA1 抗体 (ab67402)
Key features and details
- Rabbit polyclonal to KA1
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-KA1 antibody
KA1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to KA1 -
由来種
Rabbit -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat -
免疫原
Synthetic peptide corresponding to Mouse KA1 aa 1-18 (C terminal). An 18 amino acid synthetic peptide near the carboxy terminus of the mouse Grik4.
(Peptide available asab209614) -
ポジティブ・コントロール
- Rat brain lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Allow to warm to room temp and agitate gently before aliquotting. Store at -20°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Positive Controls
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab67402の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | (1) |
特記事項 |
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WB: Use at a concentration of 0.5 - 2 µg/ml. Detects a band of approximately <97 kDa (predicted molecular weight: 108 kDa).
N.B. KA1 often migrates at a lower molecular weight in SDS-PAGE.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
ターゲット情報
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機能
Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. -
配列類似性
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK4 subfamily. -
細胞内局在
Cell membrane. Cell junction > synapse > postsynaptic cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 24406 Rat
- SwissProt: Q01812 Rat
- Unigene: 10049 Rat
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別名
- EAA 1 antibody
- EAA1 antibody
- Excitatory amino acid receptor 1 antibody
see all
画像
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Lane 1 : Anti-KA1 antibody (ab67402) at 0.5 µg/ml
Lane 2 : Anti-KA1 antibody (ab67402) at 1 µg/ml
Lane 3 : Anti-KA1 antibody (ab67402) at 2 µg/ml
All lanes : Rat brain lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 108 kDa
Observed band size: <97 kDa why is the actual band size different from the predicted?
N.B. KA1 often migrates at a lower molecular weight in SDS-PAGE.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab67402 は 1 報の論文で使用されています。
- Bonnet CS et al. AMPA/kainate glutamate receptor antagonists prevent posttraumatic osteoarthritis. JCI Insight 5:N/A (2020). PubMed: 32544091