Anti-Junctional Adhesion Molecule 1/JAM-A 抗体 (ab91501)
Key features and details
- Goat polyclonal to Junctional Adhesion Molecule 1/JAM-A
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-Junctional Adhesion Molecule 1/JAM-A antibody
Junctional Adhesion Molecule 1/JAM-A 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Junctional Adhesion Molecule 1/JAM-A -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cat, Dog, Pig -
免疫原
Synthetic peptide corresponding to Human Junctional Adhesion Molecule 1/JAM-A aa 282-295 (C terminal).
Sequence:C-QPSARSEGEFKQTS
Database link: NP_058642.1 -
ポジティブ・コントロール
- Human peripheral bood mononucleocyte lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% Tris buffered saline, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
ab91501 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab91501の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use a concentration of 0.3 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 33 kDa).
A 1 hour primary incubation is recommended for this product. |
特記事項 |
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WB
Use a concentration of 0.3 - 2 µg/ml. Detects a band of approximately 38 kDa (predicted molecular weight: 33 kDa). A 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. -
配列類似性
Belongs to the immunoglobulin superfamily.
Contains 2 Ig-like V-type (immunoglobulin-like) domains. -
翻訳後修飾
N-glycosylated. -
細胞内局在
Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells. - Information by UniProt
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参照データベース
- Entrez Gene: 50848 Human
- Entrez Gene: 16456 Mouse
- Entrez Gene: 116479 Rat
- Omim: 605721 Human
- SwissProt: Q9Y624 Human
- SwissProt: O88792 Mouse
- SwissProt: Q9JHY1 Rat
- Unigene: 517293 Human
see all -
別名
- CD 321 antibody
- CD321 antibody
- CD321 antigen antibody
see all
画像
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Anti-Junctional Adhesion Molecule 1/JAM-A antibody (ab91501) at 0.3 µg/ml + Human Peripheral Blood Mononucleocyte lysate at 35 µg
Predicted band size: 33 kDa
Observed band size: 38 kDa why is the actual band size different from the predicted?
The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab91501 は論文での使用が確認できていません。