Anti-Junctional Adhesion Molecule 1 抗体 (ab106114)

製品の概要

• 製品名
  Anti-Junctional Adhesion Molecule 1 antibody
  Junctional Adhesion Molecule 1 一次抗体 製品一覧
• 製品の詳細
  Rabbit polyclonal to Junctional Adhesion Molecule 1
• アプリケーション
  適用あり: WB, IHC-P, Flow Cytmore details
  適用なし: ELISA
• 種交差性
  交差種: Human
  非交差種: Mouse
• 免疫原

  Extracellular domain of full-length Human Junctional Adhesion Molecule 1.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• バッファー
  Preservative: 0.02% Sodium Azide
  Constituents: 0.1% BSA, PBS
• Concentration information loading...
• 精製度
  Protein A purified
• 特記事項（精製）
  0.2 µm filtered antibody solution
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Cardiovascular
  • Blood
  • Platelets

  • Signal Transduction
  • Cytoskeleton / ECM
  • Cell Adhesion
  • Tight Junctions

  • Cardiovascular
  • Atherosclerosis
  • Vascular Inflammation
  • Leukocyte recruitment
  • Cell junction molecules

関連製品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

アプリケーション

ターゲット情報

• 機能
  Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
• 配列類似性
  Belongs to the immunoglobulin superfamily.
  Contains 2 Ig-like V-type (immunoglobulin-like) domains.
• 翻訳後修飾
  N-glycosylated.
• 細胞内局在
  Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.

• Target information above from: UniProt accession Q9Y624 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 50848 Human
  • Omim: 605721 Human
  • SwissProt: Q9Y624 Human
  • Unigene: 517293 Human
• 別名
  • CD 321 antibody
  • CD321 antibody
  • CD321 antigen antibody

  • ESTM33 antibody
  • F11 receptor antibody
  • F11R antibody
  • JAM 1 antibody
  • JAM A antibody
  • JAM antibody
  • JAM-1 antibody
  • JAM-A antibody
  • JAM1 antibody
  • JAM1_HUMAN antibody
  • JAMA antibody
  • JCAM antibody
  • Jcam1 antibody
  • Junction adhesion molecule 1 antibody
  • Junction adhesion molecule, mouse, homolog of antibody
  • Junctional adhesion molecule 1 antibody
  • Junctional adhesion molecule A antibody
  • KAT antibody
  • Ly106 antibody
  • PAM 1 antibody
  • PAM-1 antibody
  • PAM1 antibody
  • Platelet adhesion molecule 1 antibody
  • Platelet adhesion molecule antibody
  • Platelet F11 receptor antibody
  • PRO301 antibody
  • UNQ264 antibody

  see all

プロトコール

• Flow cytometry protocols
• Immunohistochemistry protocols
• Western blot protocols