製品の概要
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製品名Anti-Junctional Adhesion Molecule 1 antibody
Junctional Adhesion Molecule 1 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to Junctional Adhesion Molecule 1
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由来種Rabbit
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アプリケーション適用あり: WB, IHC-P, Flow Cytmore details
適用なし: ELISA -
種交差性交差種: Human
非交差種: Mouse -
免疫原
Extracellular domain of full-length Human Junctional Adhesion Molecule 1.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS -
Concentration information loading... -
精製度Protein A purified
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特記事項（精製）0.2 µm filtered antibody solution
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab106114 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/50. Predicted molecular weight: 33 kDa. | |
| IHC-P | 1/50. | |
| Flow Cyt | 1/50. ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
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追加情報
Is unsuitable for ELISA.
ターゲット情報
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機能Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
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配列類似性Belongs to the immunoglobulin superfamily.
Contains 2 Ig-like V-type (immunoglobulin-like) domains. -
翻訳後修飾N-glycosylated.
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細胞内局在Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.
- Information by UniProt
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参照データベース
- Entrez Gene: 50848 Human
- Omim: 605721 Human
- SwissProt: Q9Y624 Human
- Unigene: 517293 Human
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別名
- CD 321 antibody
- CD321 antibody
- CD321 antigen antibody
see all
参考文献
ab106114 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"