製品の概要

  • 製品名Anti-JTB antibody
    JTB 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to JTB
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-147 of Human JTB

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab56798 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
    • 組織特異性Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts.
    • 配列類似性Belongs to the JTB family.
    • 細胞内局在Membrane. Mitochondrion. Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Detected at the centrosome and along spindle fibers during prophase and metaphase. Detected at the midbody during telophase.
    • Information by UniProt
    • 参照データベース
    • 別名
      • hJT antibody
      • HJTB antibody
      • HSPC222 antibody
      • JTB antibody
      • JTB_HUMAN antibody
      • Jumping translocation breakpoint antibody
      • Jumping translocation breakpoint protein antibody
      • OTTHUMP00000034759 antibody
      • PAR antibody
      • PAR protein antibody
      • Prostate androgen regulated protein antibody
      • Prostate androgen-regulated protein antibody
      • Protein JTB antibody
      see all

    Anti-JTB antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab56798 JTB antibody at 1ug/ml. Predicted band size of immunogen is 42 kDa

    Anti-JTB antibody (ab56798) 使用論文

    ab56798 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56798.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"