製品の概要

  • 製品名Anti-JPH1 antibody
    JPH1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to JPH1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: VADEQVTAIV NKPLMSKAPT KEAGAVVPQS KYSGRHHIPN PSNGELHSQY HGYYVKLNAP QHPPVDVEDG DGSSQSSSA, corresponding to amino acids 501-580 of Human JPH1

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57425 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH1 contributes to the construction of the skeletal muscle triad by linking the t-tubule (transverse-tubule) and SR (sarcoplasmic reticulum) membranes.
    • 組織特異性Abundantly expressed in skeletal muscle. Very low levels in heart.
    • 配列類似性Belongs to the junctophilin family.
      Contains 7 MORN repeats.
    • ドメインThe MORN (membrane occupation and recognition nexus) repeats contribute to the plasma membrane binding, possibly by interacting with phospholipids.
    • 細胞内局在Cell membrane. Endoplasmic reticulum membrane. Sarcoplasmic reticulum membrane. Localized predominantly on the plasma membrane. The transmembrane domain is anchored in endoplasmic/sarcoplasmic reticulum membrane, while the N-terminal part associates with the plasma membrane. In skeletal muscle cells, it is predominantly localized at the junction of the A and I bands.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZp762L0313 antibody
      • JP 1 antibody
      • JP-1 antibody
      • JP1 antibody
      • JPH 1 antibody
      • JPH1 antibody
      • JPH1_HUMAN antibody
      • Junctophilin 1 antibody
      • Junctophilin type 1 antibody
      • Junctophilin type1 antibody
      • Junctophilin-1 antibody
      • Junctophilin1 antibody
      • Mitsugumin 72 antibody
      • Mitsugumin72 antibody
      see all

    Anti-JPH1 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab57425 JPH1 antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    Anti-JPH1 antibody (ab57425) 使用論文

    ab57425 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57425.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"