This fast track antibody is not yet fully characterized. It is subject to these
terms and conditions
製品の概要
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製品名Anti-JMJD5 antibody
JMJD5 一次抗体 製品一覧 -
製品の詳細Rabbit polyclonal to JMJD5
This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »
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種交差性
交差が予測される動物種: Mouse, Rat, Cow, Human
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免疫原
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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バッファーPreservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 -
Concentration information loading... -
精製度Immunogen affinity purified
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
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Immunizing Peptide (Blocking)
ターゲット情報
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機能Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.
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組織特異性Weakly expressed in most cells. Highly expressed in breast cancer cells.
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配列類似性Contains 1 JmjC domain.
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細胞内局在Nucleus.
- Information by UniProt
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参照データベース
- Entrez Gene: 79831 Human
- Entrez Gene: 77035 Mouse
- Entrez Gene: 308976 Rat
- Omim: 611917 Human
- SwissProt: Q8N371 Human
- SwissProt: Q9CXT6 Mouse
- SwissProt: Q497B8 Rat
- Unigene: 145717 Human
see all -
別名
- FLJ13798 antibody
- JmjC domain-containing protein 5 antibody
- JMJD5 antibody
see all
Anti-JMJD5 antibody (ab36104) 使用論文
This product has been referenced in:
- Youn MY et al. JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation. J Biol Chem 287:12994-3004 (2012). WB ; Human . Read more (PubMed: 22375008) »
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"